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Patterns

Selenium Insufficiency

Explanation

Selenium is a mineral that plays a critical role in numerous physiological processes and metabolism. Insufficiency of this mineral may have wide-ranging implications, affecting the cardiovascular, endocrine, musculoskeletal, immune, and reproductive systems. (source)

Impact

Selenium insufficiency can impair cardiovascular health, weaken the immune system, and disrupt thyroid function and metabolic processes, which may lead to decreased work capacity and increased fatigue. Adequate selenium levels support essential physiological functions, enhancing energy metabolism, muscle function, and overall resilience. This mineral also plays a role in antioxidant defense, helping to protect against oxidative stress and promote recovery after physical exertion.

Optimization

Supplement with Selenium: Supplementation with selenium has been shown to increase selenium levels in the blood. (source) Recommendation: Supplement with at least 50 mcg of selenium daily.

Supplement with Vitamin E: Many selenium deficiencies are associated with vitamin E deficiencies. (source) Vitamin E enhances the antioxidant capacity of glutathione peroxidase, an enzyme that protects cells from damage for which selenium is a cofactor. Vitamin E and selenium work synergistically to reduce oxidative stress, so vitamin E serves to support the biological functions of selenium. (source, source, source) Recommendation: Supplement with at least 10 mg of vitamin E daily.

Associated Biomarkers