The parathyroid glands produce a hormone that maintains calcium balance in the body. Parathyroid overactivity disrupts this balance, which impacts bone, kidney function, and vitamin D metabolism. (source, source)
Parathyroid overactivity disrupts calcium balance by increasing its release from bones and reducing its excretion by the kidneys, leading to weakened bones and potential kidney stones. This imbalance can also impair vitamin D metabolism, further compromising bone health and overall performance by affecting muscle function and energy metabolism. Parathyroid health affects multiple physiological processes. Supporting parathyroid function tangentially supports optimal function throughout the body.
Supplement with Magnesium: Magnesium has been shown to be a regulator of parathyroid activity. (source) Magnesium inhibits parathyroid hormone secretion through mechanisms that involve receptor modulation and interaction with calcium. It enhances the expression of receptors that regulate parathyroid function. Through these actions, magnesium aids in reducing markers of parathyroid overactivity. (source, source) Recommendation: Supplement with at least 200 mg of magnesium daily.
Supplement with Probiotics: Probiotic use has been shown to support healthy parathyroid activity. (source) Probiotics modulate gut microbiota, enhance bone metabolism, and interact with vitamin D pathways, functions that aid in regulating parathyroid hormone levels and markers of parathyroid overactivity. (source, source) Recommendation: Supplement with at least 16 billion CFUs of probiotics that include Lactobacillus and Bifidobacterium species daily.