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Patterns

Pancreatic Insufficiency

Explanation

The pancreas produces fluids that contain digestive enzymes which are essential for the breakdown of food. Pancreatic insufficiency refers to a reduction in those enzymes needed for digestion, characterized by an inability to digest and absorb key nutrients. (source, source)

Impact

The pancreas is essential for digestion and nutrient absorption. Without proper pancreatic function, the body can't fully break down food, leading to inadequate nutrient absorption and impaired cellular processes. Supporting the pancreas ensures efficient digestion, enhancing nutrient absorption and optimizing cognitive and physical performance.

Optimization

Supplement with Digestive Enzymes: Supplementing with digestive enzymes improves pancreatic function. (source) Digestive enzymes enhance nutrient digestion and absorption, modify the intestinal microbiota, and adapt to dietary changes. These actions work together to improve digestive health and support markers of pancreatic function. (source, source) Recommendation: Supplement with digestive enzymes with meals.

Supplement with Probiotics: Probiotic supplementation has been shown to promote pancreatic health. (source) Probiotics modulate gut microbiota, enhance gut barrier integrity, regulate the immune system, and stimulate secretion of GLP-1, a hormone that regulates appetite and glucose homeostasis. These actions work together to improve markers of pancreatic function. (source, source, source) Recommendation: Supplement with at least 16 billion CFUs of probiotics that include Lactobacillus and Bifidobacterium species daily.

Associated Biomarkers