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Patterns

Insulin Resistance

Explanation

Insulin is a hormone secreted by the pancreas that helps regulate blood glucose levels. Insulin resistance is characterized by the inability of muscle, fat, and liver cells to take up glucose from the blood for energy, which may lead to higher levels of blood glucose. (source)

Impact

Insulin resistance can impair glucose uptake in brain, muscle, fat, and liver cells, leading to higher blood glucose levels, and reduced energy availability. Effective insulin regulation supports optimal glucose utilization, ensuring a steady energy supply and improved exercise performance.

Optimization

Supplement with Berberine: Berberine has been shown to improve blood sugar regulation by increasing insulin sensitivity and enhancing cellular pathways that support glucose utilization. (source, source, source, source, source) Recommendation: Supplement with at least 1 g of berberine daily.

Supplement with Chromium: Chromium has been shown to improve blood glucose control. (source) Chromium increases insulin sensitivity and enhances glucose transport ability, and it has been shown to increase the activity of AMPK, an enzyme that helps regulate metabolic processes. This results in greater utilization of glucose, helping to improve blood insulin levels. (source, source) Recommendation: Supplement with at least 200 mcg of chromium picolinate daily.

Associated Biomarkers