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Heavy Metal Exposure

Explanation

Heavy metals are naturally occurring elements that may have deleterious effects on overall health. Exposure to these elements occurs via inhalation, ingestion, or skin contact. Heavy metals produce free radicals that cause oxidative stress to cells, which negatively affects both cell structure and function. (source)

Impact

Exposure to heavy metals can negatively impact performance by inducing oxidative stress, which damages cells and disrupts vital processes like energy production, muscle function, and recovery. Addressing and mitigating heavy metal exposure through effective strategies can improve overall health and potentially enhance performance. By reducing oxidative damage, athletes may experience better energy levels, improved muscle function, and faster recovery. Thus, managing heavy metal exposure can support optimal physiological function and boost athletic capabilities.

Optimization

Supplement with Alpha-Lipoic Acid: Alpha-lipoic acid (ALA) has been shown to mitigate the impact of cellular oxidative stress. (source) Alpha-lipoic acid mitigates heavy metal exposure through its antioxidant properties, metal chelation, and modulation of cellular death and stress response pathways. These mechanisms help reduce oxidative stress, prevent cellular damage, and enhance detoxification processes. (source) Recommendation: Supplement with at least 600 mg of alpha-lipoic acid daily.

Supplement with Glutathione:  Glutathione has been shown to improve markers of heavy metal exposure. (source, source) Glutathione mitigates heavy metal exposure by reducing oxidative stress, modulating detoxifying enzyme activities, inhibiting lipid peroxidation, and facilitating detoxification through conjugation. These mechanisms help protect against heavy metal exposure. (source) Recommendation: Supplement with at least 250 mg of glutathione daily.

Associated Biomarkers