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Glutathione Need

Explanation

Glutathione is a powerful antioxidant that protects cells throughout the body from toxic injury. Glutathione is especially needed to help support the liver during times of excessive stress. (source, source)

Impact

A deficiency in glutathione can negatively impact performance by reducing the body’s ability to detoxify, leading to increased oxidative stress, slower recovery, and decreased cellular efficiency. Adequate glutathione levels protect cells from damage, support liver function, and enhance recovery, especially during times of stress, promoting efficient performance.

Optimization

Supplement with N-acetylcysteine (NAC): Consuming NAC has been shown to increase glutathione concentrations. (source) NAC increases glutathione by supplying cysteine, a necessary component for glutathione synthesis. This mechanism helps to maintain glutathione concentrations. (source, source) Recommendation: Supplement with at least 500 mg of NAC daily.

Supplement with Quality Protein Source: Amino acids from protein help support glutathione synthesis. (source) Dietary protein provides cysteine and other sulfur amino acids necessary for glutathione synthesis. (source) Recommendation: Supplement with 20 to 40 g of quality protein with a goal of consuming 0.8 to 1.2 g of protein per pound of bodyweight per day.

Associated Biomarkers