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Patterns

Excessive Skeletal Breakdown

Explanation

The skeletal system is in a constant flux of breakdown and replacement. When the balance of breakdown and replacement starts to favor skeletal breakdown, it can lead to bone fragility, compromising skeletal integrity.

Impact

Excessive skeletal breakdown leads to diminished bone mineral density. This is a reflection of mineral storage, a crucial element for cellular function. Further, excessive skeletal breakdown is related to low bone strength, which will hinder the transfer of force. Reducing skeletal breakdown and improving skeletal density supports working cells with proper mineral stores and ensures efficient force transfer for peak performance.

Optimization

Supplement with Calcium: Calcium levels are associated with bone health. (source) Calcium supplementation increases bone mineral density at common fracture sites. Calcium also stabilizes parathyroid hormone levels. High parathyroid hormone levels can lead to bone resorption, where bone is broken down to release calcium into the bloodstream. By stabilizing parathyroid hormone, calcium reduces bone resorption and supports bone density. (source) Recommendation: Supplement with at least 500 mg of calcium daily.

Vitamin D + Vitamin K2: Vitamins D and K work synergistically to elicit positive effects on bone health and metabolism. (source) Vitamin D has been shown to increase alkaline phosphatase activity and calcification genes in osteoblasts, while vitamin K2 promotes processes supporting bone mineral maturation. Together, these vitamins have been shown to significantly increase bone mineral density and decrease markers of bone turnover. (source) Recommendation: Supplement with up to 2,000 IU of vitamin D and at least 90 mcg of vitamin K daily.

Associated Biomarkers